Date: 2024-07-13

Take a look at data extracted from previous trials and longitudinal studies

  • Hammitt et al.2022: MELODY (Phase III)
  • Simões et al. 2023: phase IIb + phase III
  • Ares-Gómez et al. 2024: longitudinal study in Spain


Use data from previous trials as priors to do VE estimation

Comparing:
* Original trial estimates; * Adjusted VE estimated from current case-control study (uninformative priors); * Adjusted VE estimated from current case-control study (trial data as informative priors)

Medically attended RSV LRTI (Hammitt et al)

  • extracted from case-control: RSV+ LRTI as cases vs. RSV- LRTI as controls

Medically attended all-cause LRTI (Hammitt et al)

  • extracted from case-control: records with LRTI symptoms as cases vs. those without LRTI symptoms as controls

Compare the results